Dr Sandeep Vaishya

DR. SANDEEP VAISHYA

MBBS, MS, MCH (Neurosurgery)
Fellowship Sundt & Mayo Clinic, USA
HOD & Executive Director 

Department of Neurosurgery FMRI

Oligodendrogliomas

Oligodendrogliomas

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    Frequently Asked Questions :

    Q1: Are oligodendrogliomas curable?

    A: Low-grade oligodendrogliomas can be managed and controlled with surgery and other treatments, while high-grade tumors require more aggressive treatment. Complete remission is rare but long-term management is possible.

     

    A: Recovery time varies, but most patients can resume normal activities within 4-6 weeks after surgery, with some needing longer for full neurological recovery.

     

    A: While most cases are sporadic, some rare genetic syndromes may increase the risk of developing brain tumors. Genetic counseling may be suggested in these cases.

     

    Oligodendrogliomas

    About Oligodendrogliomas

    Oligodendrogliomas are a rare type of brain tumor that originate from oligodendrocytes, which are cells responsible for producing myelin, the protective sheath around nerve cells. These tumors are considered a type of glioma, and while they can occur at any age, they are most commonly diagnosed in adults between the ages of 30 and 50.

    As a highly regarded neurosurgeon, Dr. Sandeep Vaishya specializes in diagnosing and treating complex brain tumors like oligodendrogliomas, offering world-class care to patients globally.

    Causes of Oligodendrogliomas

    The exact causes of oligodendrogliomas are still under research, but certain genetic mutations have been linked to their development. Factors that may contribute to the formation of these tumors include:

    • Genetic Mutations: The most common mutations include alterations in the IDH1 or IDH2 genes and the co-deletion of chromosomes 1p and 19q.
    • Environmental Exposure: While no direct cause has been established, exposure to ionizing radiation has been associated with an increased risk of brain tumors.
    • Family History: Although rare, individuals with a family history of brain tumors may be at higher risk.

    Types of Oligodendrogliomas

    Oligodendrogliomas are classified based on their aggressiveness and growth rate:

    1. Grade II Oligodendroglioma (Low-Grade): These are slow-growing tumors and may cause less immediate symptoms, but they can progress over time.

    2. Grade III Oligodendroglioma (Anaplastic): These are fast-growing and more aggressive tumors, often requiring more intensive treatment.

    Symptoms of Oligodendrogliomas

    The symptoms of oligodendrogliomas vary depending on the tumor’s location in the brain. Common symptoms include:

    • Headaches: Frequent or severe headaches.
    • Seizures: A major symptom, especially in low-grade oligodendrogliomas.
    • Memory Loss: Cognitive decline or difficulty with concentration.
    • Motor Function Problems: Weakness or loss of coordination in limbs.
    • Vision Problems: Blurred or double vision.
    • Personality Changes: Mood swings or altered behavior.

    Diagnosis of Oligodendrogliomas

    Diagnosing oligodendrogliomas requires a combination of imaging tests, clinical evaluation, and biopsy. The most common diagnostic methods include:

    • MRI Scans: Provides detailed images of the brain to identify abnormalities.
    • CT Scans: Helps visualize the tumor’s size and location.
    • Biopsy: A sample of the tumor is taken to confirm the diagnosis and grade of the tumor.
    • Genetic Testing: Helps identify specific genetic markers (like 1p/19q co-deletion) to tailor treatment plans.

    Treatment for Oligodendrogliomas

    Treatment for oligodendrogliomas is personalized based on the grade and location of the tumor. Dr. Sandeep Vaishya offers the following treatment options:

    1. Surgery: The primary treatment for oligodendrogliomas is surgical removal. Dr. Vaishya uses minimally invasive techniques to safely remove as much of the tumor as possible.

    2. Radiation Therapy: Post-surgery, radiation may be used to target any remaining tumor cells.

    3. Chemotherapy: Chemotherapy, often with a drug called temozolomide, is used to treat high-grade or recurring tumors.

    4. Targeted Therapy: For patients with specific genetic mutations, targeted therapies that attack tumor-specific markers may be an option.

    Cost of Oligodendroglioma Treatment and Stay in India

    India has become a leading destination for high-quality and affordable medical care. The cost of treatment for oligodendrogliomas in India is significantly lower compared to Western countries, without compromising on the quality of care.

    • Cost of Surgery: Ranges between $6,000 to $10,000 USD, depending on the complexity of the case.
    • Hospital Stay: Patients typically need to stay in the hospital for 5-7 days post-surgery, and a recovery period of 2-3 weeks in India is recommended.
    • Accommodation: Affordable accommodation options near hospitals are available, ranging from $30 to $100 USD per day.
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